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found that silencing NLRP3 could reverse the high glucose-induced upregulation of NLRP3, caspase-1, IL-1, IL-18, and ICAM-1, and they further found that ROS scavengers could reverse the high glucose-induced upregulation of IL-1 and IL-18 in ECs

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You measure based on units, where 100 units equals 1 mL on a U-100 syringe